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1

Targeting pattern-recognition receptors to discover new small molecule immune modulators

Zhu, Gengzheng, Xu, Yao, Cen, Xiaohong, Nandakumar, Kutty Selva, Liu, Shuwen, Cheng, Kui

Journal:

European Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.65 MB

english, 2018

2

Metformin, AMPK activator inhibits activation of fibroblast-like synoviocytes but promotes hyaluronan and proteoglycan link protein 1 secretion

Chen, Yong, Qiu, Fujuan, Yu, Beijia, Chen, Yanjuan, Zuo, Fangfang, Zhu, XiaoYu, Nandakumar, Kutty Selva, Xiao, Changhong

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2020

File:

PDF, 20.51 MB

2020

3

Emerging and state of the art hemagglutinin-targeted influenza virus inhibitors.

Zhang, Qiao, Liang, Taizhen, Nandakumar, Kutty Selva, Liu, Shuwen

Journal:

Expert Opinion on Pharmacotherapy

Year:

2020

File:

PDF, 1.23 MB

2020

4

Analysis of data from breast diseases treated with 5-alpha reductase inhibitors for benign prostatic hyperplasia

Fang, Qinghua, Chen, Peiya, Du, Ningchao, Nandakumar, Kutty Selva

Journal:

Clinical Breast Cancer

Year:

2019

Language:

english

File:

PDF, 10.67 MB

english, 2019

5

Type II collagen-specific antibodies induce cartilage damage in mice independent of inflammation

Croxford, Allyson M., Whittingham, Senga, McNaughton, Donald, Nandakumar, Kutty Selva, Holmdahl, Rikard, Rowley, Merrill J.

Journal:

Arthritis & Rheumatism

Year:

2013

Language:

english

File:

PDF, 301 KB

english, 2013

6

TLR1/2 Specific Small‐Molecule Agonist Suppresses Leukemia Cancer Cell Growth by Stimulating Cytotoxic T Lymphocytes

Cen, Xiaohong, Zhu, Gengzhen, Yang, Junjie, Yang, Jianjun, Guo, Jiayin, Jin, Jiabing, Nandakumar, Kutty Selva, Yang, Wei, Yin, Hang, Liu, Shuwen, Cheng, Kui

Journal:

Advanced Science

Year:

2019

Language:

english

File:

PDF, 2.47 MB

english, 2019

7

Vasorelaxant effect in rat aortic rings through calcium channel blockage: A preliminary in vitro assessment of a 1,3,4-oxadiazole derivative

Girish R. Bankar, K. Nandakumar, Pawan G. Nayak, Anjali Thakur, Mallikarjuna Rao Chamallamudi, Gopalan Kutty Nampurath

Journal:

Chemico-Biological Interactions

Year:

2009

Language:

english

File:

PDF, 220 KB

english, 2009

8

Reactive Oxygen Species in Psoriasis and Psoriasis Arthritis: Relevance to Human Disease

Khmaladze, Ia, Nandakumar, Kutty Selva, Holmdahl, Rikard

Journal:

International Archives of Allergy and Immunology

Year:

2015

Language:

english

File:

PDF, 331 KB

english, 2015

9

Inhibition dengue viral infection by Diasarone-I is associated with 2'O methyltransferase of NS5

Yao, Xin-gang, Ling, Yun, Guo, Song-xin, He, Shi-jun, Wang, Jin-an, Zhang, Qing, Wu, Wen-yu, Zou, Min, Zhang, Ting-ting, Nandakumar, Kutty Selva, Chen, Xiao-guang, Liu, Shu-wen

Journal:

European Journal of Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

10

Antigen-Specific Tolerization and Targeted Delivery as Therapeutic Strategies for Autoimmune Diseases

Shakya, Akhilesh Kumar, Nandakumar, Kutty Selva

Journal:

Trends in Biotechnology

Year:

2018

Language:

english

File:

PDF, 3.46 MB

english, 2018

11

Identification of arthritis promoting non-obese diabetic genes in the Cia9 locus using different genetic strategies

Klaczkowska, Dorota, Ekman, Diana, Holmdahl, Rikard, Nandakumar, Kutty Selva

Journal:

Annals of the Rheumatic Diseases

Year:

2012

Language:

english

File:

PDF, 69 KB

english, 2012

12

SNX10 (sorting nexin 10) inhibits colorectal cancer initiation and progression by controlling autophagic degradation of SRC

Zhang, Sulin, Yang, Zhiwen, Bao, Weilian, Liu, Lixin, You, Yan, Wang, Xu, Shao, Liming, Fu, Wei, Kou, Xinhui, Shen, Weixing, Yuan, Congmin, Hu, Bin, Dang, Wenzhen, Nandakumar, Kutty Selva, Jiang, Hual

Journal:

Year:

2019

Language:

english

File:

PDF, 10.75 MB

english, 2019

13

Arthritis induced with cartilage-specific antibodiesis IL-4-dependent

Kutty Selva Nandakumar, Rikard Holmdahl

Journal:

European Journal of Immunology

Year:

2006

Language:

english

File:

PDF, 427 KB

english, 2006

14

Induction of arthritis by single monoclonal IgG anti-collagen type II antibodies and enhancement of arthritis in mice lacking inhibitory FcγRIIB

Kutty Selva Nandakumar, Maria Andrén, Pernilla Martinsson, Estelle Bajtner, Silvia Hellström, Rikard Holmdahl, Sandra Kleinau

Journal:

European Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 239 KB

english, 2003

15

Pathogenic antibody recognition of cartilage

Kutty Selva Nandakumar

Journal:

Cell and Tissue Research

Year:

2010

Language:

english

File:

PDF, 232 KB

english, 2010

16

Secretory lysosome targeting and induced secretion of human soluble TNF-α receptor in murine hematopoietic cells in vivo as a principle for immunoregulation in inflammation and malignancy

Åsa C.M. Johansson, Kutty S. Nandakumar, Ann-Maj Persson, Inge Olsson, Markus Hansson

Journal:

Experimental Hematology

Year:

2009

Language:

english

File:

PDF, 829 KB

english, 2009

17

A Single Functional Group Substitution in C5a Breaks B Cell and T Cell Tolerance and Protects Against Experimental Arthritis

Kessel, Christoph, Nandakumar, Kutty S., Peters, Francis B., Gauba, Varun, Schultz, Peter G., Holmdahl, Rikard

Journal:

Arthritis & Rheumatology

Year:

2014

Language:

english

File:

PDF, 617 KB

english, 2014

18

Chronic active arthritis driven by macrophages without involvement of T cells

Hagert, Cecilia, Sareila, Outi, Kelkka, Tiina, Nandakumar, Kutty Selva, Collin, Mattias, Xu, Bingze, Guérard, Simon, Bäcklund, Johan, Jalkanen, Sirpa, Holmdahl, Rikard

Journal:

Arthritis & Rheumatology

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

19

In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012

Anders Kielland, Thomas Blom, Kutty Selva Nandakumar, Rikard Holmdahl, Rune Blomhoff, Harald Carlsen

Journal:

Free Radical Biology and Medicine

Year:

2009

Language:

english

File:

PDF, 771 KB

english, 2009

20

Role of anti-hinge antibodies in therapeutic cleavage of IgG: response to Drs. Lutz and Fumia

Kutty Selva Nandakumar, Rikard Holmdahl

Journal:

Trends in Immunology

Year:

2008

Language:

english

File:

PDF, 61 KB

english, 2008

21

Specific antibody protection of the extracellular cartilage matrix against collagen antibody–induced damage

Allyson M. Croxford, Duncan Crombie, Donald McNaughton, Rikard Holmdahl, Kutty Selva Nandakumar, Merrill J. Rowley

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 312 KB

english, 2010

22

Mouse models for rheumatoid arthritis

Anna-Karin B Lindqvist, Robert Bockermann, Åsa C.M Johansson, Kutty S Nandakumar, Martina Johannesson, Rikard Holmdahl

Journal:

Trends in Genetics

Year:

2002

Language:

english

File:

PDF, 140 KB

english, 2002

23

Collagen Type II and a Thermo-Responsive Polymer of N-Isopropylacrylamide Induce Arthritis Independent of Toll-Like Receptors: A Strong Influence by Major Histocompatibility Complex Class II and Ncf1 Genes

Akhilesh Kumar Shakya, Ashok Kumar, Dorota Klaczkowska, Malin Hultqvist, Kristin Hagenow, Rikard Holmdahl, Kutty Selva Nandakumar

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.33 MB

english, 2011

24

Enhancement of Antibody-Induced Arthritis via Toll-Like Receptor 2 Stimulation Is Regulated by Granulocyte Reactive Oxygen Species

Tiina Kelkka, Malin Hultqvist, Kutty Selva Nandakumar, Rikard Holmdahl

Journal:

The American Journal of Pathology

Year:

2012

Language:

english

File:

PDF, 1.35 MB

english, 2012

25

A Recombinant Vaccine Effectively Induces C5a-Specific Neutralizing Antibodies and Prevents Arthritis

Nandakumar, Kutty Selva, Jansson, Åsa, Xu, Bingze, Rydell, Niclas, Blom, Anna M., Holmdahl, Rikard, Feghali-Bostwick, Carol

Journal:

Year:

2010

Language:

english

File:

PDF, 2.62 MB

english, 2010

26

Analysis of data from breast diseases treated with 5-alpha reductase inhibitors for benign prostatic hyperplasia

Fang, Qinghua, Chen, Peiya, Du, Ningchao, Nandakumar, Kutty Selva

Journal:

Clinical Breast Cancer

Year:

2019

File:

PDF, 10.67 MB

2019

27

Collagen Type II-Specific Monoclonal Antibody-Induced Arthritis in Mice: Description of the Disease and the Influence of Age, Sex, and Genes

Kutty Selva Nandakumar, Lars Svensson, Rikard Holmdahl

Journal:

The American Journal of Pathology

Year:

2003

Language:

english

File:

PDF, 673 KB

english, 2003

28

Pain mechanisms in animal models of rheumatoid arthritis

Christina Christianson, Duygu BalkisBas, Rikard Holmdahl, Nandakumar Kutty Selva, Tony Yaksh, Maripat Corr, Gary Firestein, Camilla I. Svensson

Journal:

Scandinavian Journal of Pain

Year:

2010

Language:

english

File:

PDF, 55 KB

english, 2010

29

Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint

Ossipova, Elena, Cerqueira, Cátia, Reed, Evan, Kharlamova, Nastya, Israelsson, Lena, Holmdahl, Rikard, Nandakumar, Kutty, Engström, Marianne, Harre, Ulrike, Schett, Georg, Catrina, Anca I, Malmström,

Journal:

Arthritis Research & Therapy

Year:

2014

Language:

english

File:

PDF, 1.75 MB

english, 2014

30

Germinal center B cells are essential for collagen-induced arthritis

Dahdah, Albert, Habir, Katrin, Nandakumar, Kutty Selva, Saxena, Amit, Xu, Bingze, Holmdahl, Rikard, Malin, Stephen

Journal:

Arthritis & Rheumatology

Year:

2017

Language:

english

File:

PDF, 2.88 MB

english, 2017

31

Targeting IgG in Arthritis: Disease Pathways and Therapeutic Avenues

Nandakumar, Kutty

Journal:

International Journal of Molecular Sciences

Year:

2018

Language:

english

File:

PDF, 1.80 MB

english, 2018

32

Blocking of experimental arthritis by cleavage of IgG antibodies in vivo

Kutty Selva Nandakumar, Björn P. Johansson, Lars Björck, Rikard Holmdahl

Journal:

Arthritis & Rheumatism

Year:

2007

Language:

english

File:

PDF, 161 KB

english, 2007

33

Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis

Kutty Selva Nandakumar, Rikard Holmdahl

Journal:

Arthritis Research & Therapy

Year:

2006

Language:

english

File:

PDF, 1.06 MB

english, 2006

34

Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells

Kutty Selva Nandakumar, Johan Bäcklund, Mikael Vestberg…

Journal:

Arthritis Research & Therapy

Year:

2004

Language:

english

File:

PDF, 281 KB

english, 2004

35

Chemical changes demonstrated in cartilage by synchrotron infrared microspectroscopy in an antibody-induced murine model of rheumatoid arthritis

Croxford, Allyson M., Selva Nandakumar, Kutty, Holmdahl, Rikard, Tobin, Mark J., McNaughton, Don, Rowley, Merrill J.

Journal:

Journal of Biomedical Optics

Year:

2011

Language:

english

File:

PDF, 607 KB

english, 2011

36

Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection

Yao, Xingang, Guo, Songxin, Wu, Wenyu, Wang, Jinan, Wu, Shengen, He, Shijun, Wan, Yihong, Nandakumar, Kutty Selva, Chen, Xiaoguang, Sun, Ning, Zhu, Qiuhua, Liu, Shuwen

Journal:

Journal of Pharmacological Sciences

Year:

2018

Language:

english

File:

PDF, 3.61 MB

english, 2018

37

An encephalomyelitis-specific locus on chromosome 16 in mouse controls disease development and expression of immune-regulatory genes

Therese Lindvall, Kutty Selva Nandakumar, Kimia Yousefi, Rikard Holmdahl, Åsa Andersson

Journal:

Journal of Neuroimmunology

Year:

2011

Language:

english

File:

PDF, 833 KB

english, 2011

38

Genetic control of antibody production during collagen-induced arthritis development in heterogeneous stock mice

Förster, Michael, Raposo, Bruno, Ekman, Diana, Klaczkowska, Dorota, Popovic, Marjan, Nandakumar, Kutty S., Lindvall, Therese, Hultqvist, Malin, Teneva, Ivanka, Johannesson, Martina, Ahlqvist, Emma, Ho

Journal:

Arthritis & Rheumatism

Year:

2012

Language:

english

File:

PDF, 453 KB

english, 2012

39

Cartilage oligomeric matrix protein specific antibodies are pathogenic

Hui Geng, Kutty Selva Nandakumar, Anna Pramhed…

Journal:

Arthritis Research & Therapy

Year:

2012

Language:

english

File:

PDF, 1.07 MB

english, 2012

40

Regulatory role of Golgi brefeldin A resistance factor‐1 in amyloid precursor protein trafficking, cleavage and Aβ formation

Liu, Kaifei, Liu, Ying, Xu, Yanting, Nandakumar, Kutty Selva, Shen, Xiaoyan, Lin, Jiahe, Li, Cuixian, He, Chonghua, Zhou, Chun

Journal:

Journal of Cellular Biochemistry

Year:

2019

File:

PDF, 1.98 MB

2019

41

Immunotherapy for treating methamphetamine, heroin and cocaine use disorders

Xiaoshan, Tang, Junjie, Yang, Wenqing, Wang, Yunong, Zeng, Jiaping, Li, Shanshan, Lin, Kutty Selva, Nandakumar, Kui, Cheng

Journal:

Drug Discovery Today

Year:

2019

Language:

english

File:

PDF, 1.65 MB

english, 2019

42

Molecular and Cellular Pathways Contributing to Joint Damage in Rheumatoid Arthritis

Fang, Qinghua, Zhou, Chun, Nandakumar, Kutty Selva

Journal:

Mediators of Inflammation

Year:

2020

Language:

english

File:

PDF, 1.64 MB

english, 2020

43

Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen

Estelle Bajtner, Kutty S Nandakumar, Åke Engström…

Journal:

Arthritis Research & Therapy

Year:

2005

Language:

english

File:

PDF, 635 KB

english, 2005

44

Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism

Wigerblad, Gustaf, Bas, Duygu B, Fernades-Cerqueira, Cátia, Krishnamurthy, Akilan, Nandakumar, Kutty Selva, Rogoz, Katarzyna, Kato, Jungo, Sandor, Katalin, Su, Jie, Jimenez–Andrade, Juan Miguel, Finn,

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 3.90 MB

english, 2015

45

B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production

Khmaladze, Ia, Saxena, Amit, Nandakumar, Kutty Selva, Holmdahl, Rikard

Journal:

European Journal of Immunology

Year:

2015

Language:

english

File:

PDF, 1024 KB

english, 2015

46

Animal Models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in the Rat

Tuncel, Jonatan, Haag, Sabrina, Hoffmann, Markus H., Yau, Anthony C. Y., Hultqvist, Malin, Olofsson, Peter, Bäcklund, Johan, Nandakumar, Kutty Selva, Weidner, Daniela, Fischer, Anita, Leichsenring, An

Journal:

Year:

2016

Language:

english

File:

PDF, 2.70 MB

english, 2016

47

Epitope-specific recognition of type II collagen by rheumatoid arthritis antibodies is shared with recognition by antibodies that are arthritogenic in collagen-induced arthritis in the mouse

Harald Burkhardt, Tobias Koller, Åke Engström, Kutty Selva Nandakumar, Javier Turnay, Hans G. Kraetsch, Joachim R. Kalden, Rikard Holmdahl

Journal:

Arthritis & Rheumatism

Year:

2002

Language:

english

File:

PDF, 491 KB

english, 2002

48

[1,2,4]Triazolo[1,5-a]pyrimidine derivative (Mol-5) is a new NS5-RdRp inhibitor of DENV2 proliferation and DENV2-induced inflammation

Wan, Yi-hong, Wu, Wen-yu, Guo, Song-xin, He, Shi-jun, Tang, Xiao-dong, Wu, Xiao-yun, Nandakumar, Kutty Selva, Zou, Min, Li, Lin, Chen, Xiao-guang, Liu, Shu-wen, Yao, Xin-gang

Journal:

Acta Pharmacologica Sinica

Year:

2019

Language:

english

File:

PDF, 4.57 MB

english, 2019

49

Collagen antibody-induced arthritis evokes persistent pain with spinal glial involvement and transient prostaglandin dependency

Bas, Duygu B., Su, Jie, Sandor, Katalin, Agalave, Nilesh M., Lundberg, Johanna, Codeluppi, Simone, Baharpoor, Azar, Nandakumar, Kutty S., Holmdahl, Rikard, Svensson, Camilla I.

Journal:

Arthritis & Rheumatism

Year:

2012

Language:

english

File:

PDF, 925 KB

english, 2012

50

Characterization of chemically defined poly-N-isopropylacrylamide based copolymeric adjuvants

Shakya, Akhilesh Kumar, Holmdahl, Rikard, Nandakumar, Kutty Selva, Kumar, Ashok

Journal:

Year:

2013

Language:

english

File:

PDF, 2.74 MB

english, 2013

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